i have spent some hours trying to find the answer i would like to hear... fruitlessly.
B&H lists OS 10.5.6 as required for the MXO2 mini, and the Matrox site says 10.5 for the Matrox MXO2 'family' and i cannot find specifics for the mini. i am stuck at 10.5.3 for my Pro Tools 7.4.2 version and would love to avoid having to spend more for the MXO2 LE or a Pro Tools 8 upgrade (along with the grief of potential inter-program/OS bugs-all my programs are playing nicely now!!!) ...
soooooo: anyone using the Matrox MXO2 mini with 10.5.3 and final cut 6?
thanks!

Does Matrox answer the phone? I'd check direct with the source...
(800) 361-4903 in North America for the sales office, and I'd bet they could get you an answer quickly.

Hi Brian
Have asked for clarification from the dev team ... will update the thread later if/when I get it, but hopefully you'll be able to contact them or hear back from them directly before then.
Cheers
Andy

Brian,

The MXO2 family all use the same I/O and computing engine/firmware inside, it's just a matter of physical form factor and connectivity.

Here's your answer:

http://www.matrox.com/video/media/pdf/products/mac/mxo2/en_mxo2_mac_faq.pdf

All the MXO2 devices will work with 10.5 and later.

i actually live in Burundi: 800 #'s don't work and phoning 2010 from the stone age is sketchy at best- and expensive!
i have posted on the Matrox user forum also, but i see Andy Mees is tech support there too!
i will email Matrox support, but would still like to know is anyone is using this configuration...

edit: email support is only for customers with registered products...